Isoptin SR Contraindications

Hypersensitivity to verapamil hydrochloride or to any of the inactive ingredients.
Cardiogenic shock.
Second or third degree AV block (except in patients with a functioning artificial pacemaker).
Sick sinus syndrome (except in patients with a functioning artificial pacemaker).
Congestive heart failure and/or severe left ventricular dysfunction (e.g. reduced ejection fraction of less than 35%, and/or pulmonary wedge pressure above 20 mmHg), unless secondary to a supraventricular tachycardia amenable to verapamil therapy.
Atrial fibrillation/flutter in the presence of an accessory bypass tract (e.g. Wolff-Parkinson-White, Lown-Ganong-Levine syndromes). These patients are at risk to develop ventricular tachyarrhythmia including ventricular fibrillation if verapamil hydrochloride is administered.
Acute myocardial infarction with complications (bradycardia, marked hypotension, left ventricular failure) and sinoatrial block.
Combination with Ivabradine (see Interactions).